Colgate Natural Extracts Ultimate Fresh toothpaste with Lemon Oil and Aloe Extracts for a refreshing, invigorating experience with energizing citrus mint flavour. , Directions for use: Brush thoroughly with a Colgate toothbrush, at least twice a day, or as directed by a dentist or physician. Children 6 years and under should only use a pea sized amount and should be supervised by an adult to minimize swallowing.