Jarrow Formulas Methyl B-12, Methyl folate Plus Pyridoxal-5-Phosphate (P5P) combines the biologically active coenzyme forms of vitamin B-12, B-9, and B-6 to support DNA and neurotransmitter synthesis, and carbohydrate, fat, and amino acid metabolism. Methylcobalamin (Methyl B-12) and Methyl Folate are biologically active forms of vitamin B-12 and B-9. Methyl Folate is unlike synthetic folic acid that may interfere with natural folate metabolism. , , Methyl Folate is unlike synthetic folic acid that may mask vitamin B12 deficiency. Methyl Folate does not have a tolerable upper intake level established. Pyridoxal 5-Phosphate (P-5-P) Is the Coenzyme Form of Vitamin B6. Keep out of reach of children.